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Case study for Dermisil
James, Leisa, Dr
Podiatry, University College Northampton April 2000
Conclusions... A random controlled trial was conducted to compare the effectiveness of two home treatments: Melaleuca alternifolia and Salicylic acid (salactol) on the resolution rates of verrucae pedis and pain levels experienced when using a visual analogue scale. Ten subjects, (age range 16-45), with single plantar warts were randomly assigned to one of the two experimental treatment groups. Subjects received once-daily applications of either Salicylic acid (16.7%) or Melaleuca alternifolia (100%) for 12 weeks. Debridement and clinical assessment were performed at 0, 4, 8 and 12 weeks. Statistical analysis using a parametric unrelated t test revealed that no significant difference could be identified (p>0.05) when using Salicylic acid or Melaleuca alternifolia for the treatment of verrucae pedis. Therefore the null hypothesis was accepted. Statistical analysis using a nonparametric Mann-Whitney U test identified that there was a significant difference (p>0.05) when comparing the pain levels experienced when using a visual analogue scale. This concluded that there was an overall significant pain reduction when treating verrucae pedis with Melaleuca alternifolia.
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Wart Information

Warts or Verruca (the Latin word for warts), are beni gn, superficial and usually noncancerous growths that appear on various parts of the body such as the mouth, throat, surface areas of the skin, urethra, vagina (internal and external), cervix, scrotum, anus, groin and upper thigh.

 

The Cause of warts is the Human Papilloma Virus (HPV) and there are approximately 100 different types that can cause infection. Three out of four people having sex will have HPV, according to the American College of Obstetricians and Gynecologists. Bot h sexes are affected and there are various paths of transmission: One way is through sexual contact. It is for this reason that HPV is called a sexually transmitted disease or STD. The infection is spread from person to person during vaginal, anal or oral sex. Direct contact with a wart that is located above or below the waist can be transferred to another person on whatever body surface is touched by the lesion. The virus enters through a tiny break in the skin or tissue of the sexual organs. For example, if someone has a wart on their mouth, this can be spread to the other person’s genital areas by contact through oral sex. The appearance of the genital wart is that of a slightly raised soft lesion. It is likely to appear as one pimple, or in clusters, with the color of flesh. The lesion is moist because of the warm dark environment of the vagina and its secretions. These tiny small tumors also called papillomas are nontender and vary in size. They can be small in size, or can be so tiny that you cannot see them. When the urethra is affected by these lesions, there can be some blood in the urine, painful urination and changes in the urinary stream.

 

You may discover these lesions when you are bathing. You can visualize the area by using a small mirror while you are sitting on the edge of the tub and holding it slightly below the vagina. There should not be any small blisters that are fluid –filled, or very painful, because these are symptoms of a Herpes infection. Symptoms of allergic reactions include an itchy, very red rash, and are not symptoms of a warty viral lesion.

 

Facts to remember about HPV virus:

  • Treatable and requires strict adherence to medication. It takes weeks to many months for eradication. Any wart that lingers after 6 mos. Should be seen by a dermatologist, and may need to be biopsied.
  • Recurrent
  • Very active and requires the avoidance of sexual contact during treatment, and at least for 6 wks afterward.
  • Wart growth may be stimulated by the use of oral contraceptives, pregnancy or those with a weakened immune system.
  • Stop smoking if you have HPV, because this may have some impact on the development of cervical cancer.
  • Cannot be treated with antibiotics.
  • There is no permanent cure for HPV. Any wart that has resisted treatment for 6 months or longer, should have me dical attention and it may need to be biopsied.

Incubation period varies. This is defined as the duration of time that lapses from when contact is made with an infected person, and the appearance of the first wart. This period can be anywhere from one month to 1 yr. Some people are called carriers and they never develop warts but harbor the virus in their bodies. If you are single, and sexually active, it is important to be tested for HPV. Condoms can help but may not prevent skin contact from someone with warts. It is important to get a Pap Smear which is the test used to diagnose HPV. There are 30 strains of this virus that puts you at risk for cancer of the cervix and penis. Types 16 and 18 cause 70% of cervical cancers. Types 6 and 11 cause 20-25% of vulvar cancers, and 60-65% of vaginal cancer. The FDA has approved two tests that can diagnose those HPV viruses that are high risk for cancer in patients by identifying their viral DNA sequence. Ask your gynecologist for more information regarding these tests.

 

Testing for other STD’s such as Chlamydia, gonorrhea, syphilis, and HIV, should also be carried out during this time. Treatments for genital warts include Aldara, podophyllin, cauterization, and other treatments initiated by a doctor. It is important to wear a condom during and after treatment is finished, because even if the wart is gone, it remains dormant in the affected person.

 

Flat warts

Flat warts can occur on the face at any age, on the legs in women and the face in men, which are common areas of shaving that cause small cuts on the skin. These warts tend to be small, with a smooth texture. They are flesh-colored, and number from a few to as many as 100 in one area alone. Treatment varies and retin-A, salicylic acid and other agents have been used by doctors. These treatments require a prescription.

 

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Common warts

Common warts that ap pear on the back of the hands are called palmar warts. They can also grow on the fingers, or around the nails. They are a different type from that of the HPV virus that causes genital warts. These are small, but can grow larger and can have a rough or smooth feeling to them. They can be skin colored or darker. Sometimes they have black pinpoint areas at the tip of the wart which are cause by tiny blood vessels under the skin.

Transmission of the virus can take place during the time that children share toys, on the playground, on doorknobs, towels, or by shaking hands with someone who has a wart. It is possible that children are more susceptible to the virus because of their immune systems are not fully developed. Nail biting is an activity that causes damage to the area around it, and increases the risk of viral infection. Frequent handwashing is a good way of preventing spread of the virus. Use lotion on the skin regularly to prevent cracking.
Treatments such as the application of duct tape, clear nail polish or salicylic acid directly to warts are some of the current remedies.

 

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Plantar warts

Plantar warts appear on the bottom of the foot. The warm dark areas of the foot tends to allow the warts to spread. They are usually flat, because walking on the soles of the feet tends to flatten them. They can have a rough surface, are skin colored and vary in size. It is important to avoid going barefoot which increases the chance of superficial scrapes and cuts. Wear sneakers in the gym, and apply lotion to the skin to prevent dryness and cracking. There are various kinds of treatments on the market such as salicylic acid solution, as well as laser surgery. Like any other treatment for warts, these are not guaranteed to work all of the time.

 

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